Sam KaramHealthcare TechnologyExecutive & Innovator
Leading enterprise cloud transformations and telehealth innovations in healthcare, life sciences, and finance. Expert in AWS solutions, FDA compliance, and scaling technology teams that deliver measurable business impact.
About Sam
Healthcare Technology Leader
Dynamic technology executive with 20+ years of experience leading enterprise cloud, AWS-based transformations, and P&L delivery in healthcare, life sciences, and finance. I've built and scaled global technology and product teams to deliver $258M+ strategic telehealth contracts, drive $2.3M+/year in cloud cost savings, and secured SOC2, HITRUST, FDA 510K Class II, and ISO 13485 compliance.
Expert in aligning technology strategy with C-level business goals, forging partner ecosystems, and delivering high-impact AWS solutions that improve care outcomes, revenue, and operational efficiency.
Currently offering fractional CTO/CPO services, specializing in telehealth strategy, digital health solutions, and healthcare technology transformations.
Enterprise Scale
Managing $258M+ contracts & global teams
AWS Expert
57% cost reduction & 82% performance gain
Compliance
FDA, SOC2, HITRUST, ISO certified
Patent Holder
USPTO telehealth innovation
Professional Experience
Fractional CTO/CPO
2023 - PresentPortal724, AMC Health, Life365 Health
- • Leading telehealth, digital health, and RPM solution consulting
- • Advising on product architecture, go-to-market strategy, and operations
- • Developing AI/ML powered healthcare solutions including smart stethoscopes
- • Supporting VA contracting efforts and regulatory compliance
Chief Technology Officer
2021 - 2023Health Recovery Solutions
- • Led technology organization in PE-backed telehealth company
- • Restructured entire tech department into six verticals
- • Cut 26% of AWS costs within 3 months, saving $2.3M+/year
- • Achieved first SOC2 Type II certification
Chief Technology Officer
2017 - 2021AMC Health
- • Managed $258MM VA contract for end-to-end telehealth solution
- • Consolidated 5 data centers, migrating to AWS with 57% cost reduction
- • Achieved 82% improvement in application performance
- • Maintained HITRUST compliance and ISO 13485 standards
Director of Technology
2010 - 2017Optum - UnitedHealth Group
- • Built award-winning telehealth solution supporting millions of users
- • Awarded USPTO Patent US20160171168A1 for telehealth innovation
- • Grew user base from 18,350 to over 51,000 active users
- • Achieved 20% reduction in hospital readmission rates
Key Achievements
$258M Contract Success
Led end-to-end telehealth monitoring solution for VA with mobile app, AI/ML nurse dashboard, and user portal.
AWS Transformation
57% infrastructure cost reduction and 82% performance improvement through strategic cloud migration.
USPTO Patent
Sole inventor of telehealth solution patent that grew user base from 18K to 51K+ active users.
100% FDA Compliance
Perfect track record across 5 FDA audits with zero findings while maintaining HITRUST compliance.
FDA 510K Clearance
Secured Class II clearance for RPM solution supporting millions of daily active users with 53% cost reduction.
Global Impact
Led JPMorgan Chase resource tracking application saving hundreds of millions in global office consolidation.
Fractional CTO/CPO Services
Available for strategic technology leadership and healthcare innovation consulting
Expertise Areas
- Telehealth & Digital Health Strategy
- AWS Cloud Transformations
- Healthcare Compliance (FDA, HITRUST, SOC2)
- AI/ML Implementation in Healthcare
- Technology Team Leadership & Scaling
- Product Strategy & Go-to-Market
Recent Consulting
Portal724
Mobile RPM and MEMS solutions - R&D, manufacturing, regulatory
AMC Health
AI/ML powered nurse dashboard development
Life365 Health
VA RPM solicitation strategy and compliance
Smart Stethoscope
AI/ML heart and lung sound analysis for home use
Let's Transform Healthcare Technology Together
Ready to scale your healthcare technology or need strategic leadership? Let's discuss how my experience can accelerate your success.